Published in a peer-reviewed journalOriginal research

Traumatic encephalopathy syndrome

Application of new criteria to a cohort exposed to repetitive head impacts

Aaron Ritter, Guogen Shan, Arturo Montes, Rebekah Randall, Charles Bernick. 2023. British Journal of Sports Medicine.

Read the full text at PubMed CentralDOI 10.1136/bjsports-2022-105819PubMed 36517216

The medical question

How should research measure and protect a fighter’s neurological health over time?

This evidence informs questions about cumulative exposure, neurological assessment and long-term health. The Fight Medicine Research Institute examines the study design, the fighters included and the outcomes measured when developing its own research questions.

Summary

Investigators applied traumatic encephalopathy syndrome research criteria and compared MRI, cognitive and biomarker measurements between classified groups of professional fighters.

What the abstract reports

  • Of 176 professional fighters who were 35 or older or retired (110 boxers and 66 MMA fighters), 72 (41%) met the NINDS consensus criteria for traumatic encephalopathy syndrome.
  • The group meeting the criteria had lower regional brain volumes and lower scores on reaction time, psychomotor speed and Trails A.
  • Fighters meeting the criteria tended to be boxers, to have started fighting younger, to have had more professional fights and to have been knocked out more often.

Publication status and notices

Published in a peer-reviewed journal. Observational cohort analysis in British Journal of Sports Medicine. PubMed publication type: Journal Article.

No correction, retraction or expression of concern was found in PubMed, Crossref or Scite when this record was checked.

Fight Medicine Research Institute contribution

Fight Medicine Research Institute selected and catalogued this study, prepared an original research summary, verified its bibliographic details, and maintains the associated citation record.

Article details

Relationship
External research catalogued by the Fight Medicine Research Institute. The original authors, journal and DOI are unchanged.
Published online
14 December 2022
Issue date
April 2023, volume 57, issue 7
Repository date
14 December 2022 (Europe PMC first-publication date)
Date used here
14 December 2022 (Crossref publisher deposit, online publication date)
Rights
CC BY-NC 4.0. Open access under a Creative Commons Attribution-NonCommercial licence (CC BY-NC 4.0), as recorded by Europe PMC and the licence link in the source record. The licence does not cover commercial reuse. The summary on this page is Fight Medicine Research Institute’s own wording. No abstract text, figure or table from the article is reproduced here. Licence terms.
Source check
, against PubMed (NCBI), Crossref, Europe PMC and Scite. Checked under the direction of Casey C. Sears, Founder. An LLM was utilized as a research tool with direct human oversight.
Appraisal
The check covered bibliographic details, links, licence and notices. It is not a formal critical appraisal of the full paper.
Clinical review
None. This record is a research summary, not clinical education.
Funding and conflicts
See the source record for the authors’ funding and disclosures.
Catalog
FH-005, added

Cite the original work

These files cite the work by its own authors, journal and DOI. Fight Medicine Research Institute appears only in a note, as curator of this catalog page.

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